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Cover Article
A CRISPR/RfxCas13d-mediated strategy for efficient RNA knockdown in mouse embryonic development
Lin Zhang, Shi-Meng Cao, Hao Wu, Meng Yan, Jinsong Li, Ling-Ling Che
SCIENCE CHINA Life Sciences 67(11), 2024, 2297-2306
FROM CAS & CAE MEMBERS
Profile
Profile of Dr. Xiao-Jun Huang
SCIENCE CHINA Life Sciences 67(11), 2024, 2307-2308
Research Paper
Single-cell immune landscape of measurable residual disease in acute myeloid leukemia
Xiaodong Mo, Weilong Zhang, Guomei Fu, Yingjun Chang, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Mengzhu Shen, Qiuxia Wei, Changjian Yan, Xiaojun Huang
SCIENCE CHINA Life Sciences 67(11), 2024, 2309-2322
Review
COVID-19 vaccine updates for people under different conditions
Yijiao Huang, Weiyang Wang, Yan Liu, Zai Wang, Bin Cao
SCIENCE CHINA Life Sciences 67(11), 2024, 2323-2343
Molecular mechanisms of DNA lesion and repair during antibody somatic hypermutation
Qian Hao, Jinfeng Li, Leng-Siew Yeap
SCIENCE CHINA Life Sciences 67(11), 2024, 2344-2353
Role of macrophages in aortic dissection pathogenesis: insights from preclinical studies to translational prospective
Shiyi Li, Weiguo Fu, Lixin Wang
SCIENCE CHINA Life Sciences 67(11), 2024, 2354-2367
Research Paper
Whole-genome sequencing identifies novel genes for autism in Chinese trios
Suhua Chang, Jia Jia Liu, Yilu Zhao, Tao Pang, Xiangyu Zheng, Zhirui Song, Anyi Zhang, Xuping Gao, Lingxue Luo, Yanqing Guo, Jing Liu, Li Yang, Lin Lu
SCIENCE CHINA Life Sciences 67(11), 2024, 2368-2381
Activation of the PGC-1α-mediated mitochondrial glutamine metabolism pathway attenuates female offspring osteoarthritis induced by prenatal excessive prednisone
Qingxian Li, Fan Zhang, Yongguo Dai, Liang Liu, Liaobin Chen, Hui Wang
SCIENCE CHINA Life Sciences 67(11), 2024, 2382-2397
The single-cell transcriptomic landscape of the topological differences in mammalian auditory receptors
Xiangyu Ma, Xin Chen, Yuwei Che, Siyao Zhu, Xinlin Wang, Shan Gao, Jiheng Wu, Fanliang Kong, Cheng Cheng, Yunhao Wu, Jiamin Guo, Jieyu Qi, Renjie Chai
SCIENCE CHINA Life Sciences 67(11), 2024, 2398-241
RpL38 modulates germ cell differentiation by controlling Bam expression in Drosophila testis
Yang Fang, Fengchao Zhang, Fangzhen Zhao, Jiajia Wang, Xinkai Cheng, Fei Ye, Jiayu He, Long Zhao, Ying Su
SCIENCE CHINA Life Sciences 67(11), 2024, 2411-2425
Temperature regulates negative supercoils to modulate meiotic crossovers and chromosome organization
Yingjin Tan, Taicong Tan, Shuxian Zhang, Bo Li, Beiyi Chen, Xu Zhou, Ying Wang, Xiao Yang, Binyuan Zhai, Qilai Huang, Liangran Zhang, Shunxin Wang
SCIENCE CHINA Life Sciences 67(11), 2024, 2426-2443
Unveiling potential sex-determining genes and sex-specific markers in autotetraploid Carassius auratus
Kun Zhang, Xu Huang, Chongqing Wang, Xidan Xu, Xiaowei Xu, Xiaoping Dong, Qingwen Xiao, Jinhai Bai, Yue Zhou, Zhengkun Liu, Xinyi Deng, Yan Tang, Siyang Li, Enkui Hu, Wanjing Peng, Ling Xiong, Qinbo Qin, Shaojun Liu
SCIENCE CHINA Life Sciences 67(11), 2024, 2444-2458
Multi-omics analysis reveals the genetic and environmental factors in shaping the gut resistome of a keystone rodent species
Guoliang Li, Dong Zhu, Chaoyuan Cheng, Haiyan Chu, Fuwen Wei, Zhibin Zhang
SCIENCE CHINA Life Sciences 67(11), 2024, 2459-2470
Versatile and efficient mammalian genome editing with Type I-C CRISPR System of Desulfovibrio vulgaris
Pan Li, Dingcai Dong, Fei Gao, Yuyang Xie, Honglin Huang, Siwei Sun, Zhao Ma, Cheng He, Jinsheng Lai, Xuguang Du, Sen Wu
SCIENCE CHINA Life Sciences 67(11), 2024, 2471-2487
6-Phosphogluconate dehydrogenase 2 bridges the OPP and shikimate pathways to enhance aromatic amino acid production in plants
Qian Tang, Yuxin Huang, Zhuanglin Shen, Linhui Sun, Yang Gu, Huiqing He, Yanhong Chen, Jiahai Zhou, Limin Zhang, Cuihuan Zhao, Shisong Ma, Yunhai Li, Jie Wu, Qiao Zhao
SCIENCE CHINA Life Sciences 67(11), 2024, 2488-2498
Shifts in reproductive strategies in the evolutionary trajectory of plant lineages
Xin-Jian Zhang, Xian-Han Huang, Jacob B. Landis, Quan-Sheng Fu, Jun-Tong Chen, Peng-Rui Luo, Li-Juan Li, Heng-Yi Lu, Hang Sun, Tao Deng
SCIENCE CHINA Life Sciences 67(11), 2024, 2499-2510
MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber’s hereditary optic neuropathy
Rui Wang, Feixiang Bao, Manjiao Lu, Xiaoyun Jia, Jiahui Xiao, Yi Wu, Qingjiong Zhang, Xingguo Liu
SCIENCE CHINA Life Sciences 67(11), 2024, 2511-2519
Insight
Huangjing is not only a good medicine but also an affordable healthy diet
Donghong Chen, Dun Si, Jingjing Liu, Jinping Si
SCIENCE CHINA Life Sciences 67(11), 2024, 2520-2522
Letter to the editor
Unveiling the evolutionary dynamics of microRNA-targeted plant laccase genes
Rui-Rui He, Meng-Qi Lei, Yan-Zhao Feng, Jiao Xue, Yu-Chan Zhang, Yue-Qin Chen, Yang Yu
SCIENCE CHINA Life Sciences 67(11), 2024, 2523-2526
Zika virus infection induces glycometabolic disorder in northern pig-tailed macaques
Qing Li, Ren-Hua Yang, Yan Hu, Bei-Bei Tang, Ying-Jie Jiang, Chang-Bo Zheng, Tian-Zhang Song
SCIENCE CHINA Life Sciences 67(11), 2024, 2527-2529
Research Highlight
Androgens exert multifaceted functions in sex differences analyzed through single-cell transcriptome
Xinxin Tang, Yinkun Fu, Zhihui Zou, Yue Li, Ming He
SCIENCE CHINA Life Sciences 67(11), 2024, 2530-2531
Nanowire-mediated miRNA delivery
Yuan Wang, Bing Chen
SCIENCE CHINA Life Sciences 67(11), 2024, 2532-2534
NAP-seq: unveiling the hidden world of noncapped RNAs
Liang Liang, Yuanchao Xue
SCIENCE CHINA Life Sciences 67(11), 2024, 2535-2536
